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Forskningsresultat

Malmökohorterna genererar viktiga forskningsresultat

Den forskning som bedrivs med hjälp av Malmlökohorterna har genererat betydande resultat. Här redovisar vi de vetenskapliga artiklar som publicerats tillsammans med länkar till artiklarna.

2022

A Prospective Comparison of Plasma Biomarker and Traditional Risk Factor Profiles for Incident Isolated Atherosclerotic Disease and Incident Isolated Abdominal Aortic Aneurysm.

Acosta S, Fatemi S, Melander O, Engström G, Gottsäter A.
Front Cardiovasc Med. 2022 Jan 12;8:818656.     Artikel fulltext

Female Sex and Angiotensin-Converting Enzyme (ACE) Insertion/Deletion Polymorphism Amplify the Effects of Adiposity on Blood Pressure.

Chiriacò M, Tricò D, Leonetti S, Petrie JR, Balkau B, Højlund K, Pataky Z, Nilsson PM, Natali A; RISC Investigators.
Hypertension. 2022;79(1):36-46.     Artikel fulltext

The role of circulating galectin-1 in type 2 diabetes and chronic kidney disease: evidence from cross-sectional, longitudinal and Mendelian randomisation analyses.

Drake I, Fryk E, Strindberg L, Lundqvist A, Rosengren AH, Groop L, Ahlqvist E, Borén J, Orho-Melander M, Jansson PA.
Diabetologia. 2022 Jan;65(1):128-139.     Artikel fulltext

Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes.

Hindy G, Dornbos P, Chaffin MD, Liu DJ, Wang M, et al.; AMP-T2D-GENES, Myocardial Infarction Genetics Consortium; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; NHLBI TOPMed Lipids Working Group. 
Am J Hum Genet. 2022;109(1):81-96.     Artikel fulltext

Statin use and patterns of breast cancer recurrence in the Malmo Diet and Cancer Study.

Inasu M, Feldt M, Jernström H, Borgquist S, Harborg S.
Breast. 2022 Feb;61:123-128.     Artikel fulltext

Incident cardiovascular disease and long-term exposure to source-specific air pollutants in a Swedish cohort.

Carlsen HK, Andersson EM, Molnár P, Oudin A, Xu Y, Wichmann J, Spanne M, Stroh E, Engström G, Stockfelt L.
Environ Res. 2022;112698.     Artikel fulltext

Thrombotic risk determined by protein C receptor (PROCR) variants among middle-aged and older adults: a population-based cohort study.

Manderstedt E, Hallden C, Lind-Hallden C, Elf J, Svensson P, Engström G, Melander O, Baras A, Luca L, Zöller BA.
Thromb Haemost. 2022 Jan 12.     Artikel fulltext

The inverse association between a fish consumption biomarker with gingival inflammation and periodontitis a population-based study.

Ottosson F, Hultgren L, Fernandez C, Engström G, Orho-Melander M, Kennbäck C, Persson M, Demmer RT, Melander O, Klinge B, Nilsson P, Jönsson D.
J Clin Periodontol.
2022 Feb 7.       Artikel fulltext

Self-reported IBS and gastrointestinal symptoms in the general population are associated with asthma, drug consumption and a family history of gastrointestinal diseases.

Ruderstam H, Ohlsson B.
Scand J Gastroenterol. 2022 Feb 1;1-11.   Artikel fulltext

Fibroblast growth factor 23 is associated with risk of intracerebral hemorrhage.

Svensson EH, Söderholm M.
Eur J Neurol. 2022 Jan;29(1):114-120.     Artikel fulltext

Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.

Wu P, Moon JY, Daghlas I, Franco G et al.
Diabetes Care. 2022;45(1):232-240.      Artikel fulltext

Associations between long-term exposure to low-level air pollution and risk of chronic kidney disease-findings from the Malmö Diet and Cancer cohort.

Xu Y, Andersson EM, Krage Carlsen H, Molnár P, Gustafsson S, Johannesson S, Oudin A, Engström G, Christensson A, Stockfelt L.
Environ Int. 2022 Feb;160:107085.     Artikel fulltext

2021

Diet and Lifestyle Factors and Risk of Atherosclerotic Cardiovascular Disease-A Prospective Cohort Study.

Acosta S, Johansson A, Drake I.
Nutrients. 2021 Oct 27;13(11):3822.     Artikel fulltext

Carotid-Femoral Pulse Transit Time Variability Predicted Mortality and Improved Risk Stratification in the Elderly.

An DW, Muhammad IF, Li MX, Borné Y, Sheng CS, Persson M, Cai RZ, Guo QH, Wang JG, Engström G, Li Y, Nilsson PM.
Hypertension. 2021 Nov;78(5):1287-1295.     Artikel fulltext

Is Cadmium a Risk Factor for Breast Cancer - Results from a Nested Case-Control Study Using Data from the Malmö Diet and Cancer Study.

Andersson EM, Sandsveden M, Forsgard N, Sallsten G, Manjer J, Engström G, Barregard L.
Cancer Epidemiol Biomarkers Prev. 2021;30(9):1744-1752.     Artikel fulltext

No association between moist oral snuff (snus) use and oral cancer: pooled analysis of nine prospective observational studies.

Araghi M, Galanti MR, Lundberg M, Liu Z, Ye W, Lager A, Engström G, Alfredsson L, Knutsson A, Norberg M, Wennberg P, Lagerros YT, Bellocco R, Pedersen NL, Östergren PO, Magnusson C.
Scand J Public Health. 2021;49(8):833-840.     Artikel fulltext

Risk of breast cancer in relation to dietary intake of selenium and serum selenium as a marker of dietary intake: a prospective cohort study within The Malmö Diet and Cancer Study.

Bengtsson Y, Sandsveden M, Manjer J.
Cancer Causes Control. 2021;32(8):815-826.     Artikel fulltext

Leisure-time physical activities and the risk of cardiovascular mortality in the Malmö diet and Cancer study.

Bergwall S, Acosta S, Ramne S, Mutie P, Sonestedt E.
BMC Public Health. 2021 Oct 26;21(1):1948.     Artikel fulltext

Growth differentiation factor-15 is a biomarker for all-cause mortality but less evident for cardiovascular outcomes: a prospective study: Abbreviated title: GDF-15, all-cause mortality and CVD.

Bao X, Borné Y, Xu B, Orho-Melander M, Nilsson J, Melander O, Engström G.
Am Heart J. 2021;234:81-89.     Artikel fulltext

Growth differentiation factor-15 and incident chronic kidney disease: a population-based cohort study.

Bao X, Xu B, Borné Y, Orho-Melander M, Melander O, Nilsson J, Christensson A, Engström G.
BMC Nephrol. 2021;22(1):351.     Artikel fulltext

Serum zinc and dietary intake of zinc in relation to risk of different breast cancer subgroups and serum levels as a marker of intake: a prospective nested case-control study.

Bengtsson Y, Sandsveden M, Borgquist S, Manjer J.
Breast Cancer Res Treat. 2021;189(2):571-583.     Artikel fulltext

Risk of breast cancer in relation to dietary intake of selenium and serum selenium as a marker of dietary intake: a prospective cohort study within The Malmo Diet and Cancer Study.

Bengtsson Y, Sandsveden M, Manjer J.
Cancer Causes Control. 2021 Aug;32(8):815-826.     Artikel fulltext

Self-reported bowel symptoms are associated with differences in overall gut microbiota composition and enrichment of Blautia in a population-based cohort.

Brunkwall L, Ericson U, Nilsson PM, Orho-Melander M, Ohlsson B.
J Gastroenterol Hepatol. 2021;36(1):174-180.     Artikel fulltext

The Malmö Offspring Study (MOS): design, methods and first results.

Brunkwall L, Jönsson D, Ericson U, Hellstrand S, Kennbäck C, Östling G, Jujic A, Melander O, Engström G, Nilsson J, Ohlsson B, Klinge B, Orho-Melander M, Persson M, Nilsson PM.
Eur J Epidemiol. 2021;36(1):103-116.     Artikel fulltext

Swedish snus use is associated with mortality: a pooled analysis of eight prospective studies.

Byhamre ML, Araghi M, Alfredsson L, Bellocco R, Engström G, Eriksson M, Galanti MR, Jansson JH, Lager A, Lundberg M, Östergren PO, Pedersen NL, Trolle Lagerros Y, Ye W, Wennberg P, Magnusson C.
Int J Epidemiol. 2021;49(6):2041-2050.     Artikel fulltext

Vasoactive Biomarkers Associated With Long-Term Incidence of Symptomatic Peripheral Arterial Disease and Mortality.

Dakhel A, Engström G, Melander O, Acosta S, Fatemi S, Gottsäter A, Zarrouk M.
Angiology. 2021;72(6):550-555.     Artikel fulltext

Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort.

Drake I, Hindy G, Almgren P, Engström G, Nilsson J, Melander O, Orho-Melander M.
Sci Rep. 2021;11(1):6734.     Artikel fulltext

Increased risk for prostate cancer related mortality among childless men in a population-based cohort followed for up to 40 years.

Elenkov A, Giwercman A, Zhang H, Nilsson PM, Giwercman YL.
Scand J Urol. 2021;55(2):125-128.     Artikel fulltext

Impact of genetic risk score on the association between male childlessness and cardiovascular disease and mortality.

Elenkov A, Melander O, Nilsson PM, Zhang H, Giwercman A.
Sci Rep. 2021;11(1):18526.     Artikel fulltext

Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses.

Emerging Risk Factors Collaboration/EPIC-CVD/Vitamin D Studies Collaboration.
Lancet Diabetes Endocrinol. 2021;9(12):837-846.     Artikel fulltext

Fasting serum potassium and long-term mortality in healthy men.

Falk RS, Robsahm TE, Paulsen JE, Stocks T, Drake I, Heir T.
BMC Public Health. 2021;21(1):711.     Artikel fulltext

Pro B-type Natriuretic Peptide and Midregional Proadrenomedullin are Associated with Incident Carotid Stenosis During Long Term Follow-up.

Fatemi S, Acosta S, Zarrouk M, Engström G, Melander O, Gottsäter A.
J Stroke Cerebrovasc Dis. 2021;30:105403.     Artikel fulltext

Plasma proneurotensin and prediction of cause-specific mortality in a middle-aged cohort during long-term follow-up.

Fawad A, Bergmann A, Schulte J, Butt ZA, Nilsson PM, Bennet L, Orho-Melander M, Melander O.
J Clin Endocrinol Metab. 2021 Oct 19:dgab755.      Artikel fulltext

Effect of AMY1 copy number variation and various doses of starch intake on glucose homeostasis: data from a cross-sectional observational study and a crossover meal study.

Farrell M, Ramne S, Gouinguenet P, Brunkwall L, Ericson U, Raben A, Nilsson PM, Orho-Melander M, Granfeldt Y, Tovar J, Sonestedt E.
Genes Nutr. 2021 Nov 17;16(1):21.      Artikel fulltext

Replication study reveals miR-483-5p as an important target in prevention of cardiometabolic disease.

Gallo W, Ottosson F, Kennbäck C, Jujic A, Esguerra JLS, Eliasson L, Melander O.
BMC Cardiovasc Disord. 2021;21(1):162.     Artikel fulltext

Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies.

Georgakis MK, de Lemos JA, Ayers C, Wang B, Björkbacka H, Pana TA, Thorand B, Sun C, Fani L, Malik R, Dupuis J, Engström G, Orho-Melander M, Melander O, Boekholdt SM, Zierer A, Elhadad MA, Koenig W, Herder C, Hoogeveen RC, Kavousi M, Ballantyne CM, Peters A, Myint PK, Nilsson J, Benjamin EJ, Dichgans M.
JAMA Cardiol. 2021 May 1;6(5):587-592.     Artikel fulltext

Causal Effect of Adiposity Measures on Blood Pressure Traits in 2 Urban Swedish Cohorts: A Mendelian Randomization Study.

Giontella A, Lotta LA, Overton JD, Baras A, Regeneron Genetics Center, Minuz P, Melander O, Gill D, Fava C.
J Am Heart Assoc. 2021;10(13):e020405.      Artikel fulltext

Association of Thyroid Function with Blood Pressure and Cardiovascular Disease: A Mendelian Randomization. 

Giontella A, Lotta LA, Overton JD, Baras A, On Behalf Of Regeneron Genetics Center, Sartorio A, Minuz P, Gill D, Melander O, Fava C.
J Pers Med. 2021;11(12):1306.      Artikel fulltext

Clinical Evaluation of the Polygenetic Background of Blood Pressure in the Population-Based Setting. 

Giontella A, Sjögren M, Lotta LA, Overton JD, Baras A. Regeneron Genetics Center, Minuz P, Fava C,  Melander O. Hypertension. 2021;77(1):169-177.     Artikel fulltext

Association between Sugar Intake and Intima Media Thickness as a Marker for Atherosclerosis: A Cross-Sectional Study in the Malmö Diet and Cancer Study (Sweden).

González-Padilla E, Janzi S, Ramne S, Thuneland C, Borné Y, Sonestedt E.
Nutrients. 2021;13(5):1555.     Artikel fulltext

Interaction Effect Between Copy Number Variation in Salivary Amylase Locus (AMY1) and Starch Intake on Glucose Homeostasis in the Malmö Diet and Cancer Cohort.

Hamid AK, Andersson-Assarsson J, Ericson U, Sonestedt E.
Front Nutr. 2021 Jan 7;7:598850.      Artikel fulltext

Circulating lipids and breast cancer prognosis in the Malmö diet and cancer study.

Harborg S, Ahern TP, Feldt M, Rosendahl AH, Cronin-Fenton D, Melander O, Borgquist S.
Breast Cancer Res Treat. 2021 Nov 25.      Artikel fulltext

Dietary Data in the Malmö Offspring Study-Reproducibility, Method Comparison and Validation against Objective Biomarkers.

Hellstrand S, Ottosson F, Smith E, Brunkwall L, Ramne S, Sonestedt E, Nilsson PM, Melander O, Orho-Melander M, Ericson U.
Nutrients. 2021;13(5):1579.      Artikel fulltext

Single Nucleotide Polymorphisms in Close Proximity to the Fibroblast Growth Factor 21 (FGF21) Gene Found to Be Associated with Sugar Intake in a Swedish Population.

Janzi S, González-Padilla E, Najafi K, Ramne S, Ahlqvist E, Borné Y, Sonestedt E.
Nutrients. 2021 Nov 5;13(11):3954.     Artikel fulltext

Waist circumference and a body shape index and prostate cancer risk and mortality.

Jochems SHJ, Wood AM, Häggström C, Orho-Melander M, Stattin P, Stocks T.
Cancer Med. 2021;10(8):2885-2896.     Artikel fulltext

Modifiable and Non-Modifiable Risk Factors for Atherothrombotic Ischemic Stroke among Subjects in the Malmö Diet and Cancer Study.

Johansson A, Drake I, Engström G, Acosta S.
Nutrients. 2021;13(6):1952.     Artikel fulltext

Antibodies against phosphorylcholine in hospitalized versus non-hospitalized obese subjects.

Jujić A, Korduner J, Holm H, Engström G, Bachus E, Bhattacharya P, Nilsson PM, Frostegård J, Magnusson M.
Sci Rep. 2021;11(1):20246.      Artikel fulltext

Plasma S1P (Sphingosine-1-Phosphate) Links to Hypertension and Biomarkers of Inflammation and Cardiovascular Disease: Findings From a Translational Investigation.

Jujic A, Matthes F, Vanherle L, Petzka H, Orho-Melander M, Nilsson PM, Magnusson M, Meissner A.
Hypertension. 2021;78(1):195-209.     Artikel fulltext

Glucose-Dependent Insulinotropic Peptide in the High-Normal Range Is Associated With Increased Carotid Intima-Media Thickness.

Jujić A, Nilsson PM, Atabaki-Pasdar N, Dieden A, Tuomi T, Franks PW, Holst JJ, Torekov SS, Ravassa S, Díez J, Persson M, Ahlqvist E, Melander O, Gomez MF, Groop L, Magnusson M.
Diabetes Care. 2021;44(1):224-230.       Artikel fulltext

Novel insights into peptide amidation and amidating activity in the human circulation.

Kaufmann P, Bergmann A, Melander O.
Sci Rep. 2021;11(1):15791.     Artikel fulltext

Proteomic and Metabolomic Characterization of Metabolically Healthy Obesity: A Descriptive Study from a Swedish Cohort.

Korduner J, Nilsson PM, Melander O, Gerl MJ, Engström G, Bachus E, Magnusson M, Ottosson F.
J Obes. 2021;2021:6616983.     Artikel fulltext

Machine Learning-Derived Echocardiographic Phenotypes Predict Heart Failure Incidence in Asymptomatic Individuals.

Kobayashi M, Huttin O, Magnusson M, Ferreira JP, Bozec E, Huby A-C, Preud'homme G, Duarte K, Lamiral Z, Dalleau K, Bresso E, Smaïl-Tabbone M, Devignes M-D, Nilsson PM, Leosdottir M, Boivin J-M, Zannad F, Rossignol P, Girerd N, STANISLAS study.
JACC Cardiovasc Imaging. 2021 Sep 8;S1936-878X(21)00556-8.    Artikel fulltext

Early life factors in relation to albuminuria and estimated glomerular filtration rate based on cystatin C and creatinine in adults from a Swedish population-based cohort study.

Laucyte-Cibulskiene A, Sharma S, Christensson A, Nilsson PM.
Journal of Nephrology. 2021 Oct 8.      Artikel fulltext

Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes: Meta-Analyses and Mendelian Randomization Analyses.

Lind L, Gigante B, Borné Y, Feldreich T, Leppert J, Hedberg P, Östgren CJ, Nyström FH, Sundström J, Ärnlöv J, Baldassarre D, Tremoli E, Veglia F, Hamsten A, O'Donnell CJ, Franceschini N, Orho-Melander M, Nilsson J, Melander O, Engström G, Mälarstig A.
Arterioscler Thromb Vasc Biol. 2021;5;41(5):1777-1788.     Artikel fulltext

Clinical risk scores for the prediction of incident atrial fibrillation: a modernized review.

Louka AM, Tsagkaris C, Stoica A.
Rom J Intern Med. 2021 Nov 20;59(4):321-327.     Artikel fulltext

Regeneron Genetics Center. The genomics of heart failure: design and rationale of the HERMES consortium.

Lumbers RT, Shah S, Lin H, Czuba T et al.
ESC Heart Fail. 2021 Sep 3.      Artikel fulltext

Diabetes Mellitus as a Risk Factor for Trigger Finger – a Longitudinal Cohort Study Over More Than 20 Years.

Löfgren JP, Zimmerman M, Dahlin LB, Nilsson PM, Rydberg M.
Frontiers in Clinical Diabetes and Healthcare. 2021;2:708721.     Artikel fulltext

Thrombomodulin (THBD) gene variants and thrombotic risk in a population-based cohort study.

Manderstedt E, Halldén C, Lind-Halldén C, Elf J, Svensson PJ, Engström G, Melander O, Baras A, Lotta LA, Zöller B; Regeneron Genetics Center.
J Thromb Haemost.
2021 Dec 30.      Artikel fulltext

Comparison of cardiovascular disease and cancer prevalence between Mediterranean and north European middle-aged populations (The Cilento on Ageing Outcomes Study and The Malmö Offspring Study).

Melander O, Antonini P, Ottosson F, Brunkwall L, Gallo W, Nilsson PM, Orho-Melander M, Pacente G, D'Arena G, Di Somma S.
Intern Emerg Med. 2021;16(6):1567-1572.    Artikel fulltext

The risk of chronic kidney disease in relation to anthropometric measures of obesity: A Swedish cohort study.

Memarian E, Nilsson PM, Zia I, Christensson A, Engström G.
BMC Nephrol. 2021;22(1):330.     Artikel fulltext

Evaluating drug targets through human loss-of-function genetic variation.

Minikel EV, Karczewski KJ, Martin HC, Cummings BB, Whiffin N, Rhodes D, Alföldi J, Trembath RC, van Heel DA, Daly MJ. Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Schreiber SL, MacArthur DG.
Nature. 2020;581(7809):459-464.     Artikel fulltext

Comparison of risk factors for ischemic stroke and coronary events in a population-based cohort.

Muhammad IF, Borné Y, Zaigham S, Söderholm M, Johnson L, Persson M, Melander O, Engström G.
BMC Cardiovasc Disord. 2021;21(1):536.     Artikel fulltext

Metabolic factors and the risk of small intestine cancers: pooled study of 800 000 individuals in the Metabolic syndrome and Cancer project.

Nagel G, Bjørge T, Jaensch A, Peter RS, Häggström C, Lang A, Engeland A, Teleka S, Jirström K, Lindquist D, Stattin P, Ulmer H, Concin H, Stocks T.
Int J Cancer. 2021;149(1):66-74.     Artikel fulltext

Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight.

NCD Risk Factor Collaboration (NCD-RiskC), Lurilli MLC, Zhou B, Bennett JE et al.
eLife. 2021 Mar 9;10:e60060. doi: 10.7554/eLife.60060.     Artikel fulltext

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants.

NCD Risk Factor Collaboration (NCD-RiskC), Zhou B, Carrillo-Larco RM, Danaei G et al.
Lancet. 2021;398(10304):957-980.     Artikel fulltext

Proteomic profiling reveals novel biomarkers and pathways in yype 2 diabetes risk.

Ngo D, Benson MD, Long JZ, Chen ZZ, Wang R, Nath AK, Keyes MJ, Shen D, Sinha S, Kuhn E, Morningstar JE, Shi X, Peterson BD, Chan C, Katz DH, Tahir UA, Farrell LA, Melander O, Mosley JD, Carr SA, Vasan RS, Larson MG, Smith JG, Wang TJ, Yang Q, Gerszten RE.
JCI Insight. 2021;6(5):144392.     Artikel fulltext

Gastrointestinal Symptoms and Irritable Bowel Syndrome Are Associated With Female Sex and Smoking in the General Population and With Unemployment in Men.

Nilsson D, Ohlsson B.
Front Med (Lausanne). 2021 Sep 1;8:646658.     Artikel fulltext

Promoting athero-protective immunity by vaccination with low density lipoprotein-derived antigens.

Nilsson J, Shah PK.
Atherosclerosis.2021;335:89-97.     Artikel fulltext

Exploring and comparing definitions of healthy vascular ageing in the population: characteristics and prospective cardiovascular risk.

Nilsson Wadström B, Engström G, Nilsson PM.
J Hum Hypertens. 2021;35(5):428-436.     Artikel fulltext

Associations of carbohydrates and carbohydrate-rich foods with incidence of type 2 diabetes.

Olsson K, Ramne S, González-Padilla E, Ericson U, Sonestedt E.
Br J Nutr. 2021;126(7):1065-1075.     Artikel fulltext

A plasma lipid signature predicts incident coronary artery disease.

Ottosson F, Emami Khoonsari P, Gerl MJ, Simons K, Melander O, Fernandez C.
Int J Cardiol. 2021;331:249-254.     Artikel fulltext

The associations between red cell distribution width and plasma proteins in a general population.

Pan J, Borné Y, Orho-Melander M, Nilsson J, Melander O, Engström G.
Clin Proteomics. 2021;18(1):12.     Artikel fulltext

Clustering of blood cell count abnormalities and future risk of death.

Patti G, Lio V, Di Martino G, Ricci F, Renda G, Melander O, Engström G, Hamrefors V, De Caterina R, Fedorowski A.
Eur J Clin Invest. 2021;51(8):e13562.     Artikel fulltext

Gut microbiota composition in relation to intake of added sugar, sugar-sweetened beverages and artificially sweetened beverages in the Malmö Offspring Study.

Ramne S, Brunkwall L, Ericson U, Gray N, Kuhnle GGC, Nilsson PM, Orho-Melander M, Sonestedt E.
Eur J Nutr. 2021;60(4):2087-2097.     Artikel fulltext

Long-Term Exposure to Transportation Noise and Risk of Incident Stroke: A Pooled Study of Nine Scandinavian Cohorts.

Roswall N, Pyko A, Ögren M, Oudin A et al.
Environ Health Perspect. 2021;129(10):107002.      Artikel fulltext

Metabolic factors and the risk of Dupuytren’s disease: data from 30,000 individuals followed for over 20 years.

Rydberg M, Zimmerman M, Persson J, Gottsäter A, Nilsson PM, Melander O, Dahlin LB.
Sci Rep. 2021;11:14669.     Artikel fulltext

Low thyroid hormone receptor alpha-2 (THRα-2) tumor expression is associated with unfavorable tumor characteristics and high breast cancer mortality.

Sandsveden M, Borgquist S, Rosendahl AH, Manjer J.
Breast Cancer Res. 2021;23(1):117.     Artikel fulltext

Association of mammographic features with molecular breast tumor profiles.

Sartor H, Zackrisson S, Hegardt C, Larsson C.
Cancer Treat Res Commun. 2021;28:100387.     Artikel fulltext

Copeptin as a predictive marker of incident heart failure.

Schill F, Timpka S, Nilsson PM, Melander O, Enhörning S.
ESC Heart Fail. 2021;8(4):3180-3188.     Artikel fulltext

An Insulin Resistance Score Improved Diabetes Risk Assessment in the Malmo Prevention Project-A Longitudinal Population-Based Study of Older Europeans.

Shiffman D, Louie JZ, Meigs JB, Devlin JJ, McPhaul MJ, Melander O.
Diabetes Care. 2021 Aug 6;44(10):e186-7.     Artikel fulltext

Dairy Consumption, Lactase Persistence, and Mortality Risk in a Cohort From Southern Sweden.

Sonestedt E, Borné Y, Wirfält E, Ericson U.
Front Nutr. 2021 Nov 24;8:779034.      Artikel fulltext

Circulating Growth Differentiation Factor 15 Levels Are Associated With Risk of Both Intracerebral and Subarachnoid Hemorrhage.

Song L, Söderholm M, Svensson EH, Borné Y, Engström G.
Front Neurol. 2021;12:664010.     Artikel fulltext

Development of an EAT-Lancet index and its relation to mortality in a Swedish population.

Stubbendorff A, Sonestedt E, Ramne S, Drake I, Hallström E, Ericson U.
Am J Clin Nutr. 2021 Nov 13:nqab369.     Artikel fulltext

Hyperglycaemia-associated Caspase-3 predicts diabetes and coronary artery disease events.

Sun J, Singh P, Österlund J, Orho-Melander M, Melander O, Engström G, Edsfeldt A.
J Intern Med. 2021;290(4):855-865.     Artikel fulltext

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction.

Sun J, Wang Y, Folkersen L, Borné Y, Amlien I, Buil A, Orho-Melander M, Børglum AD, Hougaard DM;  Regeneron Genetics Center, Melander O, Engström G, Werge T, Lage K.
Nat Commun. 2021;12(1):5276.     Artikel fulltext

High levels of autoantibodies against apoB100 p210 are associated with lower incidence of atrial fibrillation in women.

Sveen KA, Smith G, Björkbacka H, Orho-Melander M, Engström G, Gonçalves I, Melander O, Nilsson J, Bengtsson E.
J Intern Med. 2021 Sep 16.      Artikel fulltext

Associations Between Endometriosis and Gut Microbiota.

Svensson A, Brunkwall L, Roth B, Orho-Melander M, Ohlsson B.
Reprod Sci. 2021;28(8):2367-2377.      Artikel fulltext

Hyperglycemia and arterial stiffness across two generations.

Taimour S, Gottsäter A, Jujic A, Nilsson P.
J Hypertens. 2021;39:471–475.     Artikel fulltext

Association between Blood Pressure and BMI with Bladder Cancer Risk and Mortality in 340,000 men in Three Swedish Cohorts.

Teleka S, Jochems S, Häggström C, Wood A, Järvholm B, Orho-Melander M, Liedberg F, Stocks T.
Cancer Med. 2021;10(4):1431-1438.     Artikel fulltext

A possible association between early life factors and burden of functional bowel symptoms in adulthood.

Wennerberg J, Sharma S, Nilsson PM, Ohlsson  B. Scand
J Prim Health Care. 2021;39:506-514.     Artikel fulltext

The Inverse Association of Body Mass Index with Lung Cancer: Exploring Residual Confounding, Metabolic Aberrations and Within-Person Variability in Smoking.

Wood AM, Jonsson H, Nagel G, Häggström C, Manjer J, Ulmer H, Engeland A, Zitt E, Jochems SHJ, Ghaderi S, Stattin P, Bjørge T, Stocks T.
Cancer Epidemiol Biomarkers Prev. 2021;30(8):1489-1497.      Artikel fulltext

Elevated circulating follistatin associates with an increased risk of type 2 diabetes.

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Nat Commun. 2021;12(1):6486.     Artikel fulltext

Comparisons of Risk Factors for Abdominal Aortic Aneurysm and Coronary Heart Disease: A Prospective Cohort Study.

Xiao J, Borné Y, Bao X, Persson M, Gottsäter A, Acosta S, Engström G.
Angiology. 2021;72(1):24-31.     Artikel fulltext

Circulating Vimentin Is Associated With Future Incidence of Stroke in a Population-Based Cohort Study.

Xiao J, Chen L, Melander O, Orho-Melander M, Nilsson J, Borné Y, Engström G.
Stroke. 2021;52(3):937-944.     Artikel fulltext

Low lung function, sudden cardiac death and non-fatal coronary events in the general population.

Zaigham S, Eriksson KF, Wollmer P, Engström G.
BMJ Open Respir Res. 2021;8(1):e001043.     Artikel fulltext

Cardiovascular risk factors and autonomic indices in relation to fatal and non-fatal coronary events.

Zambach C, Fedorowski A, Borné Y, Johnson LSB, Gerward S, Hamrefors V, Engström G.
Open Heart. 2021;8(1):e001445.      Artikel fulltext

Chronic stress and poor sleeping habits are associated with self-reported IBS and poor psychological well-being in the general population.

Zejnelagic J, Ohlsson B.
BMC Res Notes.
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Anthropometric measures and the risk of developing atrial fibrillation: a Swedish Cohort Study.

Zia I, Johnson L, Memarian E, Borné Y, Engström G.
BMC Cardiovasc Disord. 2021 Dec 18;21(1):602.     Artikel fulltext

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Neighborhood socioeconomic status and aortic stenosis: A Swedish study based on nationwide registries and an echocardiographic screening cohort.

Andell P, Li X, Martinsson A, Nilsson PM, Zöller B, Smith JG, Sundquist K.
Int J Cardiol. 2020;318:153-159.     Artikel fulltext

Lymphocyte antigen 6 superfamily member D is a marker of urothelial and squamous differentiation: implications for risk stratification of bladder cancer.

Andersson N, Ohlsson J, Wahlin S, Nodin B, Boman K, Lundgren S, Jirström K.
Biomark Res. 2020;8:51.     Artikel fulltext

Effects of tumor-specific CAP1 expression and body constitution on clinical outcomes in patients with early breast cancer.

Bergqvist M, Elebro K, Sandsveden M, Borgquist S, Rosendahl AH.
Breast Cancer Res. 2020 Jun 19;22(1):67.     Artikel fulltext

Intake of fibre and plant foods and the risk of abdominal aortic aneurysm in a large prospective cohort study in Sweden.

Bergwall S, Acosta S, Sonestedt E.
Eur J Nutr. 2020;59(5):2047-2056.      Artikel fulltext

Statin use, HMGCR expression, and breast cancer survival - The Malmo Diet and Cancer Study.

Bjarnadottir O, Feldt M, Inasu M, Bendahl PO, Elebro K, Kimbung S, Borgquist S.
Sci Rep. 2020 Jan 17;10(1):558.     Artikel fulltext

Alpha-amylase 1A copy number variants and the association with memory performance and Alzheimer's dementia.

Byman E, Nägga K, Gustavsson AM; Netherlands Brain Bank, Andersson-Assarsson J, Hansson O, Sonestedt E, Wennström M.
Alzheimers Res Ther. 2020;12(1):158.     Artikel fulltext

High water intake and low urine osmolality are associated with favorable metabolic profile at a population level: low vasopressin secretion as a possible explanation.

Brunkwall L, Ericson U, Nilsson PM, Enhörning S.
Eur J Nutr. 2020;59(8):3715-3722.     Artikel fulltext

Early and Supernormal Vascular Aging: Clinical Characteristics and Association With Incident Cardiovascular Events.

Bruno RM, Nilsson PM, Engström G, Wadström BN, Empana JP, Boutouyrie P, Laurent S.
Hypertension. 2020;76(5):1616-1624.     Artikel fulltext

Sex-Specific Associations of Circulating Uric Acid with Risk of Diabetes Incidence: A Population-Based Cohort Study from Sweden.

Chen N, Muhammad IF, Li Z, Nilsson PM, Borné Y.
Diabetes Metab Syndr Obes. 2020;13:4323-4331.     Artikel fulltext

Evidence for a protective role of placental growth factor in cardiovascular disease.

Chen Y, Nilsson AH, Goncalves I, Edsfeldt A, Engström G, Melander O, Orho-Melander M, Rauch U, Tengryd C, Venuraju SM, Lahiri A, Liang C, Nilsson J.
Sci Transl Med. 2020;12(572):eabc8587.     Artikel fulltext

A structural variation reference for medical and population genetics.

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Transcript expression-aware annotation improves rare variant interpretation.

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Nature. 2020;581:452-458.     Artikel fulltext

Adherence to a Western dietary pattern and risk of bladder cancer: A pooled analysis of 13 cohort studies of the Bladder Cancer Epidemiology and Nutritional Determinants international study.

Dianatinasab M, Wesselius A, Salehi-Abargouei A, Yu EYW, Brinkman M, Fararouei M, van den Brandt P, White E, Weiderpass E, Le Calvez-Kelm F, Gunter M, Huybrechts I, Liedberg F, Skeie G, Tjonneland A, Riboli E, Giles GG, Milne RL, Zeegers MP.
Int J Cancer. 2020 Dec 15;147(12):3394-3403.     Artikel fulltext

Lifestyle and cancer incidence and mortality risk depending on family history of cancer in two prospective cohorts.

Drake I, Dias JA, Teleka S, Stocks T, Orho-Melander M.
Int J Cancer.
2020;146(5):1198-1207.     Artikel fulltext

Incretin hormones, insulin, glucagon and advanced glycation end products in relation to cognitive function in older people with and without diabetes, a population-based study.

Dybjer E, Engström G, Helmer C, Nägga K, Rorsman P, Nilsson PM.
Diabet Med. 2020;37(7):1157-1166.     Artikel fulltext

Male childlessness as independent predictor of risk of cardiovascular and all-cause mortality: A population-based cohort study with more than 30 years follow-up.

Elenkov A, Giwercman A, Tøttenborg SS, Bonde JPE, Glazer CH, Haervig KK, Bungum AB, Nilsson PM.
PLoS ONE. 2020;15:e0237422.     Artikel fulltext

A Health-Conscious Food Pattern Is Associated with Prediabetes and Gut Microbiota in the Malmö Offspring Study.

Ericson U, Brunkwall L, Hellstrand S, Nilsson PM, Orho-Melander M.
J Nutr. 2020;150(4):861-872.     Artikel fulltext

The absolute risk of gout by clusters of gout-associated comorbidities and lifestyle factors—30 years follow-up of the Malmö Preventive Project.

Fatima T, Nilsson PM, Turesson C, Dehlin M, Dalbeth N, Jacobsson LTH, Kapetanovic MC.
Arthritis Res Ther. 2020;22(1):244.     Artikel fulltext

Circulating protein biomarkers predict incident hypertensive heart failure independently of N-terminal pro-B-type natriuretic peptide levels.

Fernandez C, Rysä J, Ström K, Nilsson J, Engström G, Orho-Melander M, Ruskoaho H, Melander O.
ESC Heart Fail. 2020;7(4):1891-1899.     Artikel fulltext

Plasma Lipidome and Prediction of Type 2 Diabetes in the Population-Based Malmö Diet and Cancer Cohort.

Fernandez C, Surma MA, Klose C, Gerl MJ, Ottosson F, Ericson U, Oskolkov N, Ohro-Melander M, Simons K,  Melander O.
Diabetes Care. 2020;43(2):366-373.     Artikel fulltext

Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals.

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Nat Metab.
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The triglyceride-glucose index as a measure of insulin resistance and risk of obesity-related cancers.

Fritz J, Bjørge T, Nagel G, Manjer J, Engeland A, Häggström C, Concin H, Teleka S, Tretli S, Gylling B, Lang A, Stattin P, Stocks T, Ulmer H.
Int J Epidemiol. 2020;49(1):193-204.     Artikel fulltext

Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies.

Georgakis MK, de Lemos JA, Ayers C, Wang B, Björkbacka H, Pana TA, Thorand B, Sun C, Fani L, Malik R, Dupuis J, Engström G, Orho-Melander M, Melander O, Boekholdt SM, Zierer A, Elhadad MA, Koenig W, Herder C, Hoogeveen RC, Kavousi M, Ballantyne CM, Peters A, Myint PK, Nilsson J, Benjamin EJ, Dichgans M.
JAMA Cardiol. 2020;6(5):587-592.     Artikel fulltext

Association between added sugar intake and micronutrient dilution: a cross-sectional study in two adult Swedish populations.

González-Padilla E, A Dias J, Ramne S, Olsson K, Nälsén C, Sonestedt E.
Nutr Metab (Lond). 2020;17:15.     Artikel fulltext

Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline. 

Gorski M, Jung B, Li Y et al.
Kidney Int. 2020;S0085-2538(20)31239-4.     Artikel fulltext

Difference in the risk profiles of carotid-femoral pulse wave velocity: results from two community-based studies in China and Sweden.

Guo QH, Muhammad IF, Borné Y, Sheng CS, Persson M, Wang JG, Engström G, Li Y, Nilsson PM.
J Hum Hypertens. 2020;34(3):207-213.     Artikel fulltext

Midlife Atherosclerosis and Development of Alzheimer or Vascular Dementia.

Gustavsson AM, van Westen D, Stomrud E, Engström G, Nägga K, Hansson O.
Ann Neurol. 2020;87(1):52-62.     Artikel fulltext

Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study.

Hartz J, Krauss RM, Göttsater M, Melander O, Nilsson P, Mietus-Snyder M.
Int J Vasc Med. 2020;2020:4219180.     Artikel fulltext

Long-term exposure to air pollution and atherosclerosis in the carotid arteries in the Malmö diet and cancer cohort.

Hasslöf H, Molnár P, Andersson EM, Spanne M, Gustafsson S, Stroh E, Engström G, Stockfelt L.
Environ Res. 2020;191:110095.      Artikel fulltext

Lifetime Benefits and Harms of Prostate-Specific Antigen-Based Risk-Stratified Screening for Prostate Cancer.

Heijnsdijk EAM, Gulati R, Tsodikov A, Lange JM, Mariotto AB, Vickers AJ, Carlsson SV, Etzioni R.
J Natl Cancer Inst. 2020 Oct 1;112(10):1013-1020.     Artikel fulltext

Genome-Wide Polygenic Score, Clinical Risk Factors, and Long-Term Trajectories of Coronary Artery Disease.

Hindy G, Aragam KG, Ng K, Chaffin M, Lotta LA, Baras A; Regeneron Genetics Center, Drake I, Orho-Melander M, Melander O, Kathiresan S, Khera AV.
Arterioscler Thromb Vasc Biol. 2020;40(11):2738-2746.     Artikel fulltext

High circulating levels of midregional proenkephalin A predict vascular dementia: a population-based prospective study.

Holm H, Nägga K, Nilsson ED, Ricci F, Melander O, Hansson O, Bachus E, Fedorowski A, Magnusson M.
Sci Rep. 2020;10(1):8027.      Artikel fulltext

Beta-blocker therapy and risk of vascular dementia: A population-based prospective study.

Holm H, Ricci F, Di Martino G, Bachus E, Nilsson ED, Ballerini P, Melander O, Hansson O, Nägga K, Magnusson M, Fedorowski A.
Vascul Pharmacol. 2020;125-126:106649.      Artikel fulltext

Linear age-course effects on the associations between body mass index, triglycerides, and female breast and male liver cancer risk: An internal replication study of 800,000 individuals.

Häggström C, Jonsson H, Bjørge T, Nagel G, Manjer J, Ulmer H, Drake I, Ghaderi S, Lang A, Engeland A, Stattin P, Stocks T.
Int J Cancer. 2020;146(1):58-67.     Artikel fulltext

Association between dietary fiber intake and risk of incident aortic stenosis.

Janzi S, Dias JA, Martinsson A, Sonestedt E.
Nutr Metab Cardiovasc Dis. 2020;30(12):2180-2185.     Artikel fulltext

Associations Between Added Sugar Intake and Risk of Four Different Cardiovascular Diseases in a Swedish Population-Based Prospective Cohort Study.

Janzi S, Ramne S, González-Padilla E, Johnson L, Sonestedt E.
Front Nutr. 2020;7:603653.     Artikel fulltext

Protein-altering germline mutations implicate novel genes related to lung cancer development.

Ji X, Mukherjee S, Landi MT, Bosse Y et al.
Nat Commun. 2020;11(1):2220.     Artikel fulltext

Diet and Lifestyle as Risk Factors for Carotid Artery Disease: A Prospective Cohort Study.

Johansson A, Acosta S.
Cerebrovasc Dis. 2020;49(5):563-569.    Artikel fulltext

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study.

Jujić A, Atabaki-Pasdar N, Nilsson PM, Almgren P, Hakaste L, Tuomi T, Berglund LM, Franks PW, Holst JJ, Prasad RB, Torekov SS, Ravassa S, Díez J, Persson M, Melander O, Gomez MF, Groop L, Ahlqvist E, Magnusson M.
Diabetologia. 2020;63(5):1043-1054.      Artikel fulltext

Height, body mass index, and prostate cancer risk by way of detection and cancer risk category.

Jochems SHJ, Stattin P, Häggström C, Järvholm B, Orho-Melander M, Wood AM, Stocks T.
Int J Cancer. 2020;147(12):3328-3338.    Artikel fulltext

Glucose-dependent insulinotropic peptide and risk of cardiovascular events and mortality: a prospective study.

Jujić A, Atabaki-Pasdar N, Nilsson PM, Almgren P, Hakaste L, Tuomi T, Berglund LM, Franks PW, Holst JJ, Prasad RB, Torekov SS, Ravassa S, Díez J, Persson M, Melander O, Gomez MF, Groop L, Ahlqvist E, Magnusson M.
Diabetologia. 2020;63(5):1043-1054.     Artikel fulltext

Periodontal disease is associated with carotid plaque area: the Malmö Offspring Dental Study (MODS).

Jönsson D, Orho-Melander M, Demmer RT, Engström G, Melander O, Klinge B, Nilsson PM.
J Intern Med. 2020;287(3):301-309.     Artikel fulltext

The mutational constraint spectrum quantified from variation in 141,456 humans.

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Nature. 2020;581(7809):434-443.     Artikel fulltext

The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation.

Lind L, Gigante B, Borne Y, Mälarstig A, Sundström J, Ärnlöv J, Ingelsson E, Baldassarre D, Tremoli E, Veglia F, Hamsten A, Orho-Melander M, Nilsson J, Melander O, Engström G.
Atherosclerosis. 2020;295:25-30.    Artikel fulltext

Serum Iodine and Breast Cancer Risk: A Prospective Nested Case-Control Study Stratified for Selenium Levels.

Manjer J, Sandsveden M, Borgquist S.
Cancer Epidemiol Biomarkers Prev. 2020;29(7):1335-1340.    Artikel fulltext

Exploration of pathophysiological pathways for incident atrial fibrillation using a multiplex proteomic chip.

Molvin J, Jujic A,  Melander O, Pareek M, Råstam L, Lindblad U, Daka B, Leosdottir M, Nilsson P, Olsen M, Magnusson M.
Open Heart. 2020;7(1):e001190.     Artikel fulltext

Proteomic exploration of common pathophysiological pathways in diabetes and cardiovascular disease.

Molvin J, Jujić A,  Melander O, Pareek M, Råstam L, Lindblad U, Daka B, Leósdóttir M, Nilsson PM, Olsen MH, Magnusson M.
ESC Heart Fail. 2020;7(6):4151–8.     Artikel fulltext

A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease.

Molvin J, Jujic A, Nilsson PM, Leosdottir M, Lindblad U, Daka B, Bennet L, Råstam L, Lyssenko V, Magnusson M.
ESC Heart Failure. 2020;7(1):348-356.     Artikel fulltext

Different domains of self-reported physical activity and risk of type 2 diabetes in a population-based Swedish cohort: the Malmö diet and Cancer study.

Mutie PM, Drake I, Ericson U, Teleka S, Schulz CA, Stocks T, Sonestedt E.
BMC Public Health. 2020;20(1):261.    Artikel fulltext

Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: a pooled analysis of 2181 population-based studies with 65 million participants.

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Lancet. 2020;396(10261):1511-1524.     Artikel fulltext

Repositioning of the global epicentre of non-optimal cholesterol.

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Nature. 2020;582(7810):73-77.      Artikel fulltext

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries.

NCD Risk Factor Collaboration (NCD-RisC).
Int J Epidemiol. 2020;49(1):173-192.     Artikel fulltext

Can the validity of a cohort be improved by reweighting based on register data? Evidence from the Swedish MDC study.

Nilsson A, Bonander C, Strömberg U, Björk J.
BMC Public Health. 2020 Dec 17;20(1):1918.     Artikel fulltext

Metabolically Healthy Obesity (MHO) – New Research Directions for Personalised Medicine in Cardiovascular Prevention.

Nilsson PM, Korduner J, Magnusson M.
Cur Hypertens Rep. 2020;22(2):18.     Artikel fulltext

Risk prediction of future cardiac arrest by evaluation of a genetic risk score alone and in combination with traditional risk factors.

Ohlsson MA, Kennedy LMA, Juhlin T, Melander O.
Resuscitation. 2020;146:74-79.     Artikel fulltext

The gut microbiota-related metabolite phenylacetylglutamine associates with increased risk of incident coronary artery disease.

Ottosson F, Brunkwall L, Smith E, Orho-Melander M, Nilsson PM, Fernandez C, Melander O.
J Hypertens. 2020;38(12):2427-2434.     Artikel fulltext

Plasma Metabolites Associate with All-Cause Mortality in Individuals with Type 2 Diabetes.

Ottosson F, Smith E, Fernandez C, Melander O.
Metabolites. 2020;10(8):E315.     Artikel fulltext

Heart rate and premature atrial contractions at 24hECG independently predict atrial fibrillation in a population-based study.

Persson AP, Fedorowski A, Hedblad B, Persson M, Juul-Möller S, Engström G, Johnson LSB.
Heart. 2020;106(4):287-291.     Artikel fulltext

Identification of Inflammatory and Disease-Associated Plasma Proteins that Associate with Intake of Added Sugar and Sugar-Sweetened Beverages and Their Role in Type 2 Diabetes Risk.

Ramne S, Drake I, Ericson U, Nilsson J, Orho-Melander M, Engström G, Sonestedt E.
Nutrients. 2020;12(10):3129.     Artikel fulltext

Comparing Self-Reported Sugar Intake With the Sucrose and Fructose Biomarker From Overnight Urine Samples in Relation to Cardiometabolic Risk Factors.

Ramne S, Gray N, Hellstrand S, Brunkwall L, Enhörning S, Nilsson PM, Engström G, Orho-Melander M, Ericson U, Kuhnle GGC, Sonestedt E.
Front Nutr. 2020;7:62.      Artikel fulltext

Family patterns of arterial stiffness across three generations in the Malmö Offspring Study.

Rosberg EP, Nilsson PM.
J Hypertens. 2020;38(3):474-480.     Artikel fulltext

High body mass index is associated with increased risk for osteoarthritis of the first carpometacarpal joint during more than 30 years of follow-up.

Rydberg M, Dahlin LB, Gottsäter A, Nilsson P, Melander O, Zimmerman M.
RMD Open. 2020;6:e001368.     Artikel fulltext

Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden.

Rydberg M, Zimmerman M, Gottsäter A, Nilsson P, Melander O, Dahlin LB.
BMJ Open Diab Res Care. 2020;8:e001298.     Artikel fulltext

Prediagnostic serum selenium levels in relation to breast cancer survival and tumor characteristics.

Sandsveden M, Nilsson E, Borgquist S, Rosendahl AH, Manjer J.
Int J Cancer. 2020;147(9):2424-2436.     Artikel fulltext

Ovarian cancer subtypes and survival in relation to three comprehensive imaging parameters.

Sartor H, Bjurberg M, Asp M, Kahn A, Brändstedt J, Kannisto P, Jirström K.
J Ovarian Res. 2020;13(1):26.     Artikel fulltext

The association of single nucleotide polymorphisms (SNPs) with breast density and breast cancer survival: the Malmö Diet and Cancer Study.

Sartor H, Brandt J, Grassmann F, Eriksson M, Czene K, Melander O, Zackrisson S.
Acta Radiol. 2020;106(3):389-404.     Artikel fulltext

Plasma kidney injury molecule-1 (p-KIM-1) levels and deterioration of kidney function over 16 years.

Schulz CA, Engström G, Nilsson J, Almgren P, Petkovic M, Christensson A, Nilsson PM, Melander O, Orho-Melander M.
Nephrol Dial Transplant. 2020;35(2):265-273.     Artikel fulltext

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

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Nat Commun. 2020;11(1):163.      Artikel fulltext

Birth size and cancer prognosis: a systematic review and meta-analysis.

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J Dev Orig Health Dis. 2020;11(4):309-316.     Artikel fulltext

Association of TIM-1 (T-Cell Immunoglobulin and Mucin Domain 1) With Incidence of Stroke.

Song L, Sun J, Söderholm M,  Melander O, Orho-Melander M, Nilsson J, Borné Y, Engström G.
Arterioscler Thromb Vasc Biol. 2020;40(7):1777-1786.     Artikel fulltext

Altered Acylcarnitine Metabolism Is Associated With an Increased Risk of Atrial Fibrillation.

Smith E, Fernandez C, Melander O, Ottosson F.
J Am Heart Assoc. 2020;9(21):e016737.     Artikel fulltext

Ergothioneine is associated with reduced mortality and decreased risk of cardiovascular disease.      

Smith E, Ottosson F, Hellstrand S, Ericson U, Orho-Melander M, Fernandez C, Melander O.
Heart. 2020;106(9):691-697.     Artikel fulltext

Does early life programming influence arterial stiffness and central hemodynamics in adulthood?

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J Hypertens. 2020;38(3):481-488.     Artikel fulltext

Mammographic tumour appearance is related to clinicopathological factors and surrogate molecular breast cancer subtype.

Sturesdotter L, Sandsveden M, Johnson K, Larsson AM, Zackrisson S, Sartor H.
Sci Rep. 2020 Nov 30;10(1):20814.     Artikel fulltext

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.

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Risk factors for intracerebral haemorrhage - Results from a prospective population-based study.

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Eur Stroke J. 2020;5(3):278-285.     Artikel fulltext

Patterns of urinary albumin and IgM associate with markers of vascular ageing in young to middle-aged individuals in the Malmö offspring study.

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BMC Cardiovasc Disord. 2020;20(1):358    Artikel fulltext

Blood cadmium concentration and risk of subarachnoid haemorrhage.

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Environ Res. 2020;180:108826.     Artikel fulltext

Low Levels of CD4+CD28null T Cells at Baseline Are Associated With First-Time Coronary Events in a Prospective Population-Based Case-Control Cohort.

Tomas L, Bengtsson E, Andersson L, Badn W, Tengryd C, Persson A, Edsfeldt A, Nilsson PM, Schiopu A, Nilsson J, Gonçalves I. Björkbacka H.
Arterioscler Thromb Vasc Biol. 2020;40(2):426-436.     Atikel fulltext

Blood pressure and bladder cancer risk in men by use of survival analysis and in interaction with NAT2 genotype, and by Mendelian randomization analysis.

Teleka S, Hindy G, Drake I, Poveda A,  Melander O, Liedberg F, Orho-Melander M, Stocks T.
PLoS One. 2020;15(11):e0241711.     Artikel fulltext

Probabilistic Quantification Of Bias to Combine the Strengths Of Population-Based Register Data and Clinical Cohorts - Studying Mortality in Osteoarthritis.

Turkiewicz A, Nilsson PM, Kiadaliri A.
Am J Epidemiol. 2020;189(12):1590-1599.     Artikel fulltext

Negative associations for fasting blood glucose, cholesterol and triglyceride levels with the development of giant cell arteritis.

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Rheumatology (Oxford). 2020 Nov 1;59(11):3229-3236.     Artikel fulltext

The effect of LRRK2 loss-of-function variants in humans.

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Nat Med. 2020;26(6):869-877.     Artikel fulltext

Investigating the risk of breast cancer among women exposed to chemicals: a nested case-control study using improved exposure estimates.

Videnros C, Selander J, Wiebert P, Albin M, Plato N, Borgquist S, Manjer J, Gustavsson P.
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Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis. 

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Red Cell Distribution Width is Associated with Future Incidence of Abdominal Aortic Aneurysm in a Population-Based Cohort Study.

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Low lung function and the risk of incident chronic kidney disease in the Malmö Preventive Project cohort.     

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Mendelian randomization analysis does not support causal associations of birth weight with hypertension risk and blood pressure in adulthood.

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